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In early 2023, based on the analysis of the medical records of approximately 6 million subjects, it was shown that prior SARS-CoV-2 infection elevated the risk of developing a wide range of autoimmune diseases, including rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus, dermatopolymyositis, systemic sclerosis, Sjögren’s syndrome, mixed connective tissue disease, Behçet’s disease, rheumatic polymyalgia, vasculitis, psoriasis, inflammatory bowel disease, celiac disease, and type 1 diabetes (13)
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In addition to producing ROS, mitochondria are also a target for ROS which, in turn, reduces mitochondrial efficiency and leads to the generation of more ROS, a vicious self-destructive cycle